Diseases, Conditions, Syndromes

Cascade of events leading to prion disease described

Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...

Medical research

Protein-trapped sugar compounds nourish infant gut microbes

UC Davis researchers have shown that an enzyme produced by beneficial microbes in babies' intestines is able to harvest specific sugar compounds from human breast-milk and cow's milk. The discovery identifies those sugars—rather ...

Medical research

Finding a way forward in the fight against prion disease

For much of her adult life Valerie Sim has been fascinated by a disease very few in the world can claim to even begin to understand. Sim is one of Canada's foremost authorities on prion disease—more commonly known as bovine ...

Medical research

Prion protein protects against epilepsy

In the most systematic and rigorous study conducted thus far in its field, the prion protein (PrPC) was clearly shown to play a role in preventing the onset of epileptic seizures. PrPC is perhaps best known in its 'degenerate' ...

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