Immunology

Overcoming immune suppression to fight against bovine leukemia

Bovine leukemia is a systemic, malignant lymphosarcoma in cows which is mainly caused by infection with a retrovirus, bovine leukemia virus (BLV). In 2016, 3,125 cases of bovine leukemia were reported in Japan, which was ...

Parkinson's & Movement disorders

Untangling fibril formation and dissociation in Parkinson's disease

Prions are misfolded proteins. The complex three-dimensional structure of a prion's progenitor protein becomes altered, somehow causing it to malfunction. Worse, the malformation of these progenitor proteins into prions causes ...

Diseases, Conditions, Syndromes

Cascade of events leading to prion disease described

Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...

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