Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of ...
Feb 12, 2015
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When integrins let go of their ligands and the actin cytoskeleton inside the dendritic cell, the activity of another cell surface receptor, the GM-CSF receptor, rises. This increased signaling induces the dendritic cells ...
Oct 29, 2014
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A surprise discovery that overturns decades of thinking about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent diseases such as Alzheimer's and Parkinson's, which have ...
Oct 16, 2014
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People with mutations in a gene called BSCL2 suffer from a rare medical condition known as lipodystrophy in which fat tissue is lost from where it is supposed to accumulate while being deposited at unusual sites around the ...
Feb 12, 2014
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(Medical Xpress)—A new study by University of Kentucky Markey Cancer Center researchers Min Chen and Kathleen O'Connor shows that a specific protein may assist breast cancer cells in metastasizing.
Oct 29, 2013
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Researchers studying a type of cell found in the trillions in our brain have made an important discovery as to how it responds to brain injury and disease such as stroke. A University of Bristol team has identified proteins ...
Jul 25, 2013
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(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined into narrow neuritic ...
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. A category ...
May 6, 2013
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How do nerve cells—which can each be up to three feet long in humans—keep from rupturing or falling apart?
Apr 15, 2013
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Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers.
Mar 15, 2013
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