Medical research

How DNA damage turns immune cells against cancer

Cancer is essentially a disease of the cell replication cycle. The goal of treating the disease is to permanently kill off the cells that replicate with abandon without any molecular brakes. Chemotherapy and radiation cause ...

Genetics

An enzyme that fixes broken DNA sometimes destroys it instead

Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some ...

Oncology & Cancer

DNA damage leads to genetic diseases and cancer

Scientists have reported that many inheritance mutations are caused by DNA damage rather than errors in DNA doubling. The study was conducted by an international research group and published in Nature Genetics.

Oncology & Cancer

How red wine prevents cancer

Alcohol use is a major risk factor for head and neck cancer. But an article published in the November issue of the journal Advances in Experimental Medicine and Biology shows that the chemical resveratrol found in grape skins ...

Medical research

Bone drug protects stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

Genetics

DNA changes during pregnancy persist into childhood

Even before they are born, babies accumulate changes in their DNA through a process called DNA methylation that may interfere with gene expression, and in turn, their health as they grow up. But until now it's been unclear ...

Medical research

Scientists establish model of Hutchinson-Gilford Progeria Syndrome

Scientists from A*STAR's Institute of Medical Biology (IMB) have successfully established a comprehensive model of rare accelerated ageing syndrome Hutchinson-Gilford Progeria Syndrome (HGPS), thereby opening up the possibility ...

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