Genetics

Immune cells identified as key players in brain health

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding ...

Oncology & Cancer

Chronic cell death promotes liver cancer

Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now, it was not known how these events are linked at the molecular level. An international team of scientists ...

Medical research

Mitochondrial mutations and disease

Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.

Genetics

Regulatory RNA essential to DNA damage response

Stanford researchers have found that a tumor suppressor known as p53 is stabilized by a regulatory RNA molecule called DINO. The interaction helps a cell respond to DNA damage and may play a role in cancer development and ...

page 29 from 40