The busy world inside a cell is directed by its DNA blueprint. When the blueprints are altered, cells can sicken, die or become cancerous. To keep DNA in working order, cells have ways to detect and mend damaged DNA.
Nov 8, 2017
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When cells multiply and migrate, they can be compressed and their nucleus may break open. This phenomenon causes DNA damage. Scientists from the CNRS, Institut Curie and INSERM have now shown that this facilitates the spread ...
Sep 23, 2021
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Researchers from the University of Southampton have established that eggs have a protective 'checkpoint' that helps to prevent DNA damaged eggs being fertilised.
Nov 2, 2015
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Our DNA is under constant attack from many sources, including environmental pollutants, ultraviolet light, and radiation. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to ...
Apr 22, 2014
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Cell aging, or cellular senescence, has an important role in the natural physiological response to tumor development. Activated oncogenes are able to induce senescence, and recent findings have suggested that oncogene-induced ...
Dec 12, 2012
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A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique. Consequently, cells with mutated p53 have a survival advantage, which can cause cancer. Researchers at Karolinska ...
Nov 18, 2021
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Every day our DNA is under attack.
Feb 27, 2015
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When it comes to using radiation against lung cancer, preliminary clinical studies were pretty clear: More is better. So why did a large phase 3 clinical trial find exactly the opposite—that stage III non-small cell lung ...
Jun 26, 2019
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Scientists led by a group of researchers at The Scripps Research Institute (TSRI) in La Jolla, CA, have discovered some of the key proteins involved in one type of DNA repair gone awry.
May 22, 2014
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Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. Current treatment options, including ...
Dec 16, 2016
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