In the 1970s, epidemiologists found that workers in factories using vinyl chloride, the key ingredient for PVC plastics, had unusually high rates of a rare form of liver cancer called angiosarcoma.
Apr 2, 2015
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The genome of a cell is under constant attack, suffering DNA damage that requires an army of repair mechanisms to keep the cell healthy and alive. Understanding the behavior of the enzymes defending these assaults helps determine ...
Mar 17, 2015
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Researchers in the UC Department of Cancer Biology have found new protein players that help keep genome stability—a promising finding with the potential to help with the development of new targeted therapeutics in diseases ...
Mar 10, 2015
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In a study just published in the journal Nature, scientists at the Deutsches Krebsforschungszentrum Heidelberg and at the Institute for Stem Cell Technology and Experimental Medicine have uncovered that environmental stress ...
Feb 18, 2015
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The Food and Drug Administration's recent approval of the drug olaparib for ovarian cancer patients with inherited mutations in the genes BRCA1 or BRCA2 came as welcome news to the thousands of women now eligible to receive ...
Feb 16, 2015
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A new study from MIT reveals one reason why people who suffer from chronic inflammatory diseases such as colitis have a higher risk of mutations that cause cancer. The researchers also found that exposure to DNA-damaging ...
Jan 16, 2015
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Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some ...
Nov 26, 2014
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Scientists from the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have learned new details about how an important tumor-suppressing protein, called p53, binds to the human genome. As with ...
Nov 24, 2014
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When tissues are deprived of blood, as happens during a stroke or heart attack, the lack of oxygen can cause serious damage. After blood flow is restored, further damage occurs as the tissues become inflamed. This process, ...
Oct 28, 2014
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A new research report published in the October 2014 issue of The FASEB Journal may make the early detection of cancer as easy as a simple blood test. This test, called the "lymphocyte genome sensitivity" (LGS) test, could ...
Sep 30, 2014
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