New research has unravelled the mystery of how mitochondria—the energy generators within cells—can withstand attacks on their DNA from rogue molecules.
Apr 28, 2017
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Tuberous sclerosis complex (TSC), a genetic disorder that causes autism in about half of those affected, could stem from a defect in a basic system cells use to recycle their mitochondria, report scientists at Boston Children's ...
Oct 18, 2016
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When a heart stops beating, blood stops flowing and delivering oxygen to the brain (hypoxia) and other vital organs (ischemia). There is a small window (about 4 minutes) before the lack of blood flow begins to damage the ...
Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...
Jul 13, 2022
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Scientists may have discovered more reasons to love chocolate.
Jun 21, 2019
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Rapamycin, an FDA-approved drug that extends lifespan in several species, prevented Parkinson's disease (PD) in middle-age mice that were genetically fated to develop the incurable neurodegenerative motor disease that affects ...
Sep 16, 2015
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A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria ...
Aug 14, 2020
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As we age, our cells change and become damaged. Now, researchers at Karolinska Institutet and the Max Planck Institute for Biology of Aging have shown that aging is determined not only by the accumulation of changes during ...
Aug 21, 2013
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Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother. The study, led by researchers from the MRC Mitochondrial Biology Unit at the University ...
Jan 15, 2018
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A class of anti-retroviral drugs commonly used to treat HIV, particularly in Africa and low income countries, can cause premature ageing, according to research published today in the journal Nature Genetics. The study shows ...
Jun 26, 2011
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