Diseases, Conditions, Syndromes

Common enzyme deficiency may hinder plans to eradicate malaria

In malaria-endemic countries, 350 million people are predicted to be deficient in an enzyme that means they can suffer severe complications from taking primaquine, a key drug for treating relapsing malaria, according to a ...

Medical research

Extra chromosome 21 removed from Down syndrome cell line

(Medical Xpress)—University of Washington scientists have succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome, a condition in which the body's cells contain three ...

Cardiology

Researchers prevent heart failure in mice

(Medical Xpress)—Cardiac stress, for example a heart attack or high blood pressure, frequently leads to pathological heart growth and subsequently to heart failure. Two tiny RNA molecules play a key role in this detrimental ...

Genetics

New findings on protein misfolding

Misfolded proteins can cause various neurodegenerative diseases such as spinocerebellar ataxias (SCAs) or Huntington's disease, which are characterized by a progressive loss of neurons in the brain. Researchers of the Max ...

Medical research

Scientists map the genomic blueprint of the heart

Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic "switches" required to construct a fully functional heart from embryonic heart cells—providing new clues into the ...

Medical research

Researchers use gene therapy to restore sense of smell in mice

(Medical Xpress)—A team of scientists from Johns Hopkins and other institutions report that restoring tiny, hair-like structures to defective cells in the olfactory system of mice is enough to restore a lost sense of smell. ...

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