Boosting vaccines for the elderly with 'hyperactivators'
As we age, our immune systems start to flag, leaving us more susceptible to cancer and infections—and less responsive to vaccines and cancer immunotherapies.
Jul 12, 2024
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As we age, our immune systems start to flag, leaving us more susceptible to cancer and infections—and less responsive to vaccines and cancer immunotherapies.
Jul 12, 2024
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The puzzle of memory has intrigued philosophers and intellects for a very long time. Plato and Aristotle believed that memory was found only in the realm of the soul and the mind, but there was nothing corporeal or physical ...
Jul 5, 2024
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Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old. For more than a decade, Ofer Levy, MD, Ph.D., and David Dowling, Ph.D., in the Precision Vaccines Program ...
Jul 3, 2024
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Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. ...
Jun 26, 2024
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Researchers at the University of Turku in Finland have found a new function for an existing protein. They discovered that TIMP-1, a protein traditionally known to prevent damage to the body's cells and tissues, plays a critical ...
Jun 14, 2024
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Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from ...
Jun 7, 2024
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Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors. One reason for the ...
May 30, 2024
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With each flip you make through a deck of vocabulary word flashcards, their definitions come more quickly, more easily. This process of learning and remembering new information strengthens important connections in your brain. ...
May 23, 2024
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Researchers from the Centenary Institute and the University of Sydney have made a major discovery in vaccine science, gaining new insights into delta inulin as a crucial vaccine component. Their findings offer a promising ...
May 22, 2024
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Researchers in the Peter Gorer Department of Immunobiology have identified that features of the immune system that were previously considered to be characteristics of autoimmune diseases are normal components of the immune ...
May 17, 2024
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Dendrites (from Greek δένδρον déndron, “tree”) are the branched projections of a neuron that act to conduct the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project. Electrical stimulation is transmitted onto dendrites by upstream neurons via synapses which are located at various points throughout the dendritic arbor. Dendrites play a critical role in integrating these synaptic inputs and in determining the extent to which action potentials are produced by the neuron. Recent research has also found that dendrites can support action potentials and release neurotransmitters, a property that was originally believed to be specific to axons.
The long outgrowths on immune system dendritic cells are also called dendrites. These dendrites do not process electrical signals.
Certain classes of dendrites (i.e. Purkinje cells of cerebellum, cerebral cortex) contain small projections referred to as "appendages" or "spines". Appendages increase receptive properties of dendrites to isolate signal specificity. Increased neural activity at spines increases their size and conduction which is thought to play a role in learning and memory formation. There are approximately 200,000 spines per cell, each of which serve as a postsynaptic process for individual presynaptic axons.
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