Oncology & Cancer

Immune profile for successful cancer immunotherapy discovered

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response ...

Neuroscience

Repeated stimulation enlarges dendritic spines

Even in adult brains, new neurons are generated throughout a lifetime. In a publication in the scientific journal PNAS, a research group led by Goethe University describes plastic changes of adult-born neurons in the hippocampus, ...

Oncology & Cancer

Brain cancer vaccine effective in some patients

Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial of a personalized vaccine that targets the aggressive cancer has indicated improved survival ...

Immunology

Fetal immune system rejects the mother in preterm labor

Preterm labor, a common pregnancy complication, has long been a mystery to scientists. But a new study from UC San Francisco shows it may sometimes happen when the fetal immune system "wakes up" too early and begins to reject ...

Oncology & Cancer

Personalized ovarian cancer vaccine shows promise in pilot trial

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania. ...

Immunology

PCSK9 inhibitors have unexpected anti-inflammatory effects

PCSK9 inhibition is a new therapeutic strategy for atherosclerosis which is known to lower LDL cholesterol. Research from Karolinska Institutet, presented at the ESC Congress last year and now published in the Journal of ...

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