Oncology & Cancer

Checkpoint blockade helps only a subset of patients, why?

Although many cancer patients respond favorably to immunotherapies such as nivolumab and pembrolizumab, most patients do not. Blame for treatment failures is usually attributed to so-called "cold" tumors, those that do not ...

Medical research

New study suggests way to slow skin fibrosis in scleroderma

The prognosis for patients diagnosed with scleroderma - an autoimmune disease characterized by fibrosis of the skin - is not typically a rosy one. With limited treatment options available, those suffering from the disorder ...

Diseases, Conditions, Syndromes

Tuberculosis and HIV co-infection

The HIV virus increases the potency of the tuberculosis bacterium (Mtb) by affecting a central function of the immune system. This is the conclusion of a study carried out by researchers at Linköping University in Sweden. ...

Immunology

How the leishmania parasite sabotages the immune response

An international collaborative of researchers has identified a mechanism that allows the leishmania parasite, which causes leishmaniasis, to evade the immune system and thereby produce infection. The study, published in Immunity, ...

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