Oncology & Cancer

Protein disguise could be new target for cancer immunotherapy

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target ...

Diseases, Conditions, Syndromes

Immune cells promote proinflammatory fatty liver disease

A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as ...

Medical research

Shootin1a—the missing link underlying learning and memory

In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...

Medical research

Important factor in the development of dendritic cells identified

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease. These include the dendritic cells. Their main function is to present antigens to other immune cells, ...

Medical research

Dendritic computers: When 1 + 1 = 3

The human brain is jampacked with neurons—86 billion of them—connected in a vast, complex network that controls how we move, think, talk and make memories. Vital information is exchanged across this network through trillions ...

Neuroscience

Watching the brain learn

Understanding the cellular and molecular mechanisms underlying brain plasticity (how the brain can learn, develop and reorganize itself) is crucial for explaining many illnesses and conditions. Neurocientists from the University ...

Diseases, Conditions, Syndromes

TB study reveals potential targets to treat and control infection

Researchers at the Southwest National Primate Research Center (SNPRC) at Texas Biomedical Research Institute (Texas Biomed) may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium ...

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