Roughly 50 families scattered across the world share ultra-rare variants in a particular gene. Silent for years, the inherited mutations make themselves known when patients reach the fourth decade of life. Changes in vision ...
Jun 17, 2024
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Scientists from the Broad Institute of MIT and Harvard, Harvard Medical School, and the University of Leipzig Medical Center have shown in two independent patient cohorts when a genome sequencing is beneficial in the diagnosis ...
Jun 7, 2024
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As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup. That small 0.4% accounts for any difference between one person and another. Specific combinations of mutations ...
May 21, 2024
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By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.
May 15, 2024
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In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities ...
May 6, 2024
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In a study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense ...
Apr 30, 2024
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Researchers from Kyushu University's Faculty of Medical Sciences report on new insights into the mechanisms of how adrenal gland tumors are formed. The team identified a new type of tumor cell population that they termed ...
Apr 2, 2024
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Although Parkinson's disease has been recognized for more than 100 years, no treatments can slow or halt the disease's progress, let alone cure it. One of the major factors underlying this lack of progress is our relatively ...
Apr 2, 2024
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Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show in the journal Stem Cell Reports. When the team transplanted bone marrow stem cells from mice carrying a hereditary version of Alzheimer's ...
Mar 28, 2024
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