Oncology & Cancer

Critical pathway in cell cycle may lead to cancer development

A team of scientists at the Salk Institute for Biological Studies has identified why disruption of a vital pathway in cell cycle control leads to the proliferation of cancer cells. Their findings on telomeres, the stretches ...

Genetics

Scientists find mutation driving pediatric brain tumors

A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...

Genetics

New insights into how genes turn on and off

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent ...

Oncology & Cancer

New mutations driving malignant melanoma discovered

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously ...

Medical research

Search for epigenetic decoder leads scientists to Rett Syndrome

(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...

Medical research

Dynamics of DNA packaging helps regulate formation of heart

A new regulator for heart formation has been discovered by studying how embryonic stem cells adjust the packaging of their DNA. This approach to finding genetic regulators, the scientists say, may have the power to provide ...

Genetics

Uncovering the genome's regulatory code

Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each gene sits a short ...

Genetics

Gene link to multiple sclerosis

(Medical Xpress) -- The biological role of a gene variant implicated in multiple sclerosis (MS) has been determined by researchers at Oxford University.

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