Genetics

Scientists decipher the 3-D structure of the human genome

Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds at scales that dwarf the double ...

Genetics

DNA discovery could advance degenerative disease treatments

New research on the structure and dynamics of a branched form of DNA called a three-way junction could lead to more effectively targeted treatments for degenerative disorders like Huntington's Disease, scientists say.

Oncology & Cancer

Four-stranded DNA structures found to play role in breast cancer

Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...

Genetics

Breakable genes may promote disease and brain cell diversity

Howard Hughes Medical Institute (HHMI) researchers have identified 27 genes in brain stem cells that are prone to a type of DNA damage. The fragility of those genes could explain why they are often mutated or deleted in cancers ...

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