Mutations driving cancer development leave behind specific 'scars," so-called mutational signatures, in the genome. In principle, they allow for profiling of the cancer type and its development—but the noisy environment ...
May 9, 2018
0
2
Penn Medicine researchers have used CRISPR/Cas9 gene editing technology to isolate a key genetic feature that could cause resistance to PARP inhibitors in patients with ovarian cancer—and they've also proven they have a ...
Apr 26, 2018
0
19
Results from an important NASA experiment – in which astronaut Scott Kelly spent one year in space while his identical twin brother Mark stayed on Earth – have started to come in. Last week, a number of media outlets ...
Mar 22, 2018
0
2
An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia. Through comprehensive gene expression analyses, the team determined how one family of genes controls ...
Mar 20, 2018
0
7
Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive ...
May 17, 2017
0
2
A study of three genes associated with the development of prostate cancer found that men with inherited mutations in these genes are more likely to develop aggressive forms of the disease and die from prostate cancer at an ...
Dec 15, 2016
0
0
Inherited mutations in genes that function to repair DNA may contribute to metastatic prostate cancer more than previously recognized, according to a study out today in the New England Journal of Medicine. Though infrequent ...
Jul 6, 2016
0
3
(HealthDay)—A special genetic test might help gauge outcomes for women diagnosed with ovarian cancer, a new study suggests.
Mar 21, 2016
0
47
A team of Georgia State University researchers is fighting cancers using a combination of therapies and recently found ways that radiation could maximize responses to novel immune-based therapeutic approaches to fight cancer.
Feb 2, 2016
0
6
DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory ...
Jan 28, 2016
0
2
