A major computational analysis by scientists at the University of Sussex and The Institute of Cancer Research, London, has found a number of potential targets for drugs that exploit the inherent weaknesses of cancer cells.
Feb 24, 2015
1
37
A study that examined 17 million mutations in the genomes of 650 cancer patients concludes that large differences in mutation rates across the human genome are caused by the DNA repair machinery.
Feb 23, 2015
8
53
After finishing his PhD in molecular genetics in the late 1990s, Daniel Anderson found himself conflicted about what to do next: He enjoyed science, but wanted to find a way to have a direct impact on human health.
Feb 17, 2015
0
6
Nova Southeastern University (NSU) researchers recently discovered that, contrary to prior belief, tissues of different mammalian organs have very different abilities to repair damage to their DNA.
Feb 9, 2015
0
29
Researchers from the University of Melbourne have found that screening for bowel cancer in genetically high-risk populations should begin early.
Feb 4, 2015
0
31
Inhibiting the action of a particular enzyme dramatically slows the growth of tumor cells tied to BRCA1 and BRCA2 genetic mutations which, in turn, are closely tied to breast and ovarian cancers, according to researchers ...
Feb 2, 2015
0
58
Researchers at the University of Michigan's C.S. Mott Children's Hospital have identified a promising new target for developing new therapies for kids with high-risk neuroblastoma, according to a new study published in Molecular ...
Jan 21, 2015
0
70
Next generation sequencing in malignant pleural mesothelioma (MPM) tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation ...
Dec 17, 2014
0
0
Most patients with triple-negative breast cancer should undergo genetic testing for mutations in known breast cancer predisposition genes, including BRCA1 and BRCA2, a Mayo Clinic-led study has found. The findings come from ...
Dec 2, 2014
0
0
Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some ...
Nov 26, 2014
1
0
