Genetics
Research on mutation 'hotspots' in DNA could lead to new insights on cancer risks
New research from Indiana University has identified "hotspots" in DNA where the risk for genetic mutations is significantly elevated.
Jul 30, 2018
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Page 11 - News tagged with dna repair
Immunology
Lung cell patches its own DNA on the fly to survive influenza
Scientists at Duke University have identified one kind of lung cell that can hustle to repair its damaged DNA and survive an attack of the influenza A virus while other kinds of cells around it die in droves.
Jul 29, 2019
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Oncology & Cancer
New knowledge about DNA repair can be turned into cancer inhibitors
Researchers at the University of Copenhagen have discovered a molecular mechanism that reads so-called epigenetic information and boosts repair of lesions in our DNA. This knowledge can be used to develop new targeted cancer ...
Jun 22, 2016
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Medications
New class of drug gives hope to some ovarian cancer patients
A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build ...
May 4, 2021
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Medical research
Oxidative DNA damage repair
Oxidative stress damages DNA. Researchers in the Vetsuisse Faculty have now decoded the mechanism that repairs DNA damaged in this way. This repair mechanism could lead to less invasive approaches in cancer therapy and contribute ...
Dec 27, 2011
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Medical research
Scientists discover a combination therapy for aggressive brain tumors
Glioblastomas are the most common and most aggressive brain tumors. Their survival rate has barely increased over the last 50 years, indicating an urgent need to develop new therapeutic strategies. In a paper published this ...
Apr 12, 2021
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Neuroscience
DNA damage may cause amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most patients within ...
Sep 16, 2013
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Oncology & Cancer
Ovarian cancer patients survive longer with BRCA2 mutated in tumors
Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...
Oct 11, 2011
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Oncology & Cancer
Olaparib becomes first gene-targeted medicine to show benefits in prostate cancer
A pioneering precision medicine already licensed for breast and ovarian cancer can also slow or stop tumour growth in some men with advanced prostate cancer, a new clinical trial shows.
Dec 3, 2019
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Genetics
Study identifies new gene mutation associated with defective DNA repair and Fanconi anemia
Fanconi anemia is a rare genetic disease characterized by hematologic symptoms that include low platelet count and unusually large red blood cells. Mutations in nearly 20 genes have been identified as causative for Fanconi ...
Jul 10, 2017
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