A protein that cancer cells rely on to stave off cell death also helps them regulate DNA repair, researchers at Winship Cancer Institute of Emory University (Winship) have discovered.
Jan 3, 2018
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Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers ...
Dec 19, 2017
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A study published by IRB Barcelona in Nature Genetics demonstrates that the error (mutation) surveillance and repair system shows greater efficiency in the protein-coding regions of genes.
Nov 7, 2017
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In many metastasised types of cancer, disseminated tumours grow back despite successful chemotherapy. As a research team under the direction of the University of Bern, Switzerland, has now discovered, this is because of isolated ...
Oct 26, 2017
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A team led by Massachusetts General Hospital (MGH) investigators has identified a new cancer-causing pathway behind most cases of an aggressive type of leukemia, findings that could lead to new targeted treatment approaches. ...
Oct 3, 2017
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Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
Sep 5, 2017
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DNA is the computer code that programs every event in the body. Despite the importance of DNA fidelity, as the body develops, cells grow and replicate, DNA is constantly turned over. This repeated process can compromise the ...
Aug 31, 2017
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Cancer is mostly caused by changes in the DNA of our cells that occur over a lifetime rather than inherited traits. Identifying the causes of these mutations is a difficult challenge because many processes can result in a ...
Jul 28, 2017
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Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers involved are the ...
Jul 26, 2017
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Inhibitors of the DNA repair enzyme poly (ADP-ribose) polymerase (PARP) kill BRCA-deficient tumours, and have significant activity in single agent and combination therapy. Professor Herbie Newell, of Newcastle University ...
Jul 25, 2017
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