Oncology & Cancer

Exploiting cancer's sweet tooth to develop a treatment

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring ...

Oncology & Cancer

Targeting a rare secondary cancer in children

It's one of the most heartbreaking things Adam Green, MD, sees as a pediatric oncologist: children who beat their cancer, only to see an incurable brain tumor arise five years later.

Genetics

A new technique for correcting disease-causing mutations

Gene editing, or purposefully changing a gene's DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual's DNA for therapeutic purposes. A novel method of gene editing ...

Medications

New class of drug gives hope to some ovarian cancer patients

A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build ...

Oncology & Cancer

New cancer algorithm flags genetic weaknesses in tumors

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project. The MMRDetect clinical ...

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