Oncology & Cancer

Scientists reveal how mutations in metabolism can drive cancers

Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...

Neuroscience

Study finds that aging neurons accumulate DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. This enzyme is often diminished in both Alzheimer's ...

Medications

Countering the negative effects of a common antidepressant

Selective serotonin reuptake inhibitors, or SSRI's, are popular drugs that treat depression by increasing the amount of a neurotransmitter called serotonin in the brain. But when a common SSRI known as sertraline is taken ...

Immunology

Sensing infection, suppressing regeneration

In a new peer-reviewed publication, University of Illinois at Chicago researchers describe how the body's response to inflammation, which helps to fight many kinds of infections, also can counterproductively suppress much-needed ...

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