Oncology & Cancer

Breast cancer vaccine safely generates anti-tumor immunity

An experimental vaccine against breast cancer safely generated a strong immune response to a key tumor protein, researchers from the University of Washington School of Medicine in Seattle report in a paper published by the ...

Medical research

DNA-based vaccine guards against Zika in monkey study

An experimental DNA-based vaccine protected monkeys from infection with the birth defects-causing Zika virus, and it has proceeded to human safety trials, researchers report.

Diseases, Conditions, Syndromes

Exploring how poxviruses dismantle antiviral responses

Northwestern Medicine investigators led by Derek Walsh, Ph.D., professor of Microbiology-Immunology, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, ...

Medical research

Scientists produce 'DNA virus vaccine' to fight DNA viruses

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for ...

Diseases, Conditions, Syndromes

DNA vaccines for COVID-19 effective in mice, hamsters

Currently available COVID-19 vaccines rely on mRNA strands to teach the human immune system to recognize the SARS-CoV-2 virus. Now, researchers reporting in PLOS Neglected Tropical Diseases have reported the successful development ...

Diseases, Conditions, Syndromes

Engineered DNA vaccine protects against emerging Mayaro virus

Infections by the mosquito-borne Mayaro virus (MAYV) have largely been restricted to people who ventured into the heavily forested areas of Trinidad and Tobago and neighboring regions of South America. However, recent laboratory ...

Medical research

A cancer drug may help treat human papillomavirus infections

Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs.

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