For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases ...
Jan 18, 2018
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(Medical Xpress)—Scientists from the FMI identify how a family of proteins reads the methylation marks on the DNA so critical for cell development. These MBD proteins bind directly to methylation marks and inactivate the ...
Apr 12, 2013
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Meier-Gorlin syndrome, or MGS, is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities. In severe cases, MGS results in miscarriages and stillbirths.
Dec 15, 2020
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The appearance of malaria parasites resistant to medicines is one of the main obstacles in combating the disease. In order to slow down this phenomenon, it is essential to avoid exposing the pathogen to the same molecules. ...
Feb 18, 2015
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A heartbeat is a carefully coordinated series of electrical signals led by sodium ion channels, which tell the heart when to contract and to relax. Any disruption to these signals may lead to cardiac diseases such as an irregular ...
Apr 3, 2023
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Ongoing research at the Institute of Food Research, which is strategically funded by BBSRC, is exploring the use of virus-produced proteins that destroy bacterial cells to combat potentially dangerous microbial infections. ...
Aug 22, 2011
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Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new findings, published October ...
Oct 5, 2015
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Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths. There is a clear need to better understand the processes that enable ...
Feb 1, 2023
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Scientists have identified thousands of previously ignored genetic mutations that, although rare, likely contribute to cancer growth. The findings, which could help pave the way to new treatments, are published in PLOS Computational ...
Apr 20, 2017
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RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue ...
Jun 24, 2022
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