A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular (iMM; Lisbon, Portugal), in partnership with the company Technophage SA, has designed a simple and efficient platform that uses ...
Jul 19, 2019
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A jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including cancer, trauma and stroke.
May 15, 2019
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Novel therapies based on a process known as RNA interference (RNAi) hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused ...
Mar 5, 2019
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There is a highly sophisticated way to treat some breast and ovarian cancers—a class of drugs called PARP inhibitors, designed to exploit the very defects that make tumors with certain mutations especially deadly. Yet this ...
Jul 18, 2018
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Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be ...
May 11, 2018
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Fresh insights into changes in the brain linked to depression could pave the way for new therapies.
Feb 26, 2018
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191
Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer.
Feb 6, 2018
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Blood vessels are the supply lines of the human body, bringing nutrients and oxygen to cells and carrying away waste. Controlling the growth of these supply lines can be an effective tactic to combat several different types ...
Dec 19, 2017
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41
St. Jude Children's Research Hospital structural biologists have deciphered how the structure of the enzyme called Abl regulates its activity, enabling the enzyme to switch itself on and off. Understanding Abl's regulation ...
Sep 26, 2017
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A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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