Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric ...
Jan 2, 2024
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Sequence variants that protect against pericarditis have been discovered at a genomic locus encoding interleukin-1 immune cytokines. A newly approved drug treatment for pericarditis inhibits these cytokines, according to ...
Dec 27, 2023
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88
A study led by VA Connecticut Healthcare Center/Yale researchers reveals ancestries around the world possess a shared genetic architecture for problematic alcohol use (PAU)—habitual heavy drinking, accompanied by harmful ...
Dec 22, 2023
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140
Scientists at St. Jude Children's Research Hospital have revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases. Leucine-rich repeat kinase 2 (LRRK2) is ...
Dec 21, 2023
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A "chaperone" molecule that slows the formation of certain proteins reversed disease signs, including memory impairment, in a mouse model of Alzheimer's disease, according to a study from researchers at the Perelman School ...
Dec 20, 2023
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390
A team of anesthesiologists at the University of Michigan, working with a pair of colleagues from Tryp Therapeutics, has found, via experimentation, that rats can experience a reduction in chronic pain when given injections ...
AI models in health care are a double-edged sword, with models improving diagnostic decisions for some demographics, but worsening decisions for others when the model has absorbed biased medical data.
Dec 19, 2023
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Researchers at the Center for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are ...
Dec 18, 2023
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Results from a Phase II clinical trial indicate that psilocybin, a hallucinogenic chemical found in certain mushrooms of the genus Psilocybe, may benefit individuals with cancer and major depression. Trial participants treated ...
Dec 18, 2023
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249
A study involving 22 Parkinson's disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% ...
7 hours ago
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