A protein found in pancreatic tumors may lead to a new chemotherapy that is effective against many different kinds of cancers, but turning the discovery into a new drug has required a bit of chemistry know-how.
Feb 20, 2015
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One of diabetes' dangerous consequences is dysfunction of the single-cell layer that lines our blood vessels.
Dec 3, 2014
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Research published in the journal Nature Medicine on Monday by my team provides hope for a new approach to treating type 2 diabetes. In animal models of the disease, our treatment restores natural control of blood sugar.
Nov 6, 2014
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Many proteins undergo an assembly line-style process of glycosylation as they travel from a cellular structure called the endoplasmic reticulum (ER) to the Golgi apparatus and on through its various compartments, after which ...
Aug 27, 2014
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(Medical Xpress)—Specially engineered mice that lacked a particular gene did not gain weight when fed a typical high-fat, obesity-inducing Western diet. Yet, these mice ate the same amount as their normal counterparts that ...
Aug 5, 2014
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A network of signals active in almost all types of cancer sends the protein factories in our cells into overdrive, and may help fuel a tumour's uncontrolled growth, new research suggests.
Jul 9, 2014
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A study in The Journal of General Physiology helps explain how nicotine exploits the body's cellular machinery to promote addiction. The findings could lead to new therapies to help people quit smoking.
Dec 30, 2013
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Resolving a fundamental question in cell biology and showing off the powers of new high-resolution 3-D imaging, NIH scientists have discovered where the Golgi apparatus, which sorts newly synthesized proteins for transport ...
Dec 15, 2013
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Hereditary spastic paraplegias (HSP) are a group of hereditary diseases that result in progressive loss of motor function in the lower limbs, and mutations in many different genes have been implicated in disease progression. ...
Sep 24, 2013
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A hallmark of cancer is uncontrolled and sustained cell division. One particular overactive protein is implicated in this malfunction. EPFL scientists have discovered a complex mechanism that regulates this protein's activity ...
Aug 14, 2013
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