Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.
Nov 21, 2011
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A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer's disease. As published ...
Feb 3, 2020
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Cancer is a group of more than 100 different diseases. All are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body. Advances in genetics and molecular biology ...
Jul 8, 2016
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Researchers at the University of Hertfordshire have developed a new structural model of a protein, which makes it possible to develop more effective drugs to target diseases such as cancer, heart disease and influenza.
Jul 29, 2011
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How sildenafil, the active ingredient in Viagra, can alleviate heart problems is reported by Bochum's researchers in cooperation with colleagues from the Mayo Clinic in Rochester (Minnesota) in the journal Circulation. They ...
Dec 23, 2011
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A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of ...
Sep 27, 2011
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Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 9, 2012
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One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously. Salk Institute researchers ...
May 31, 2018
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Scientists at the Francis Crick Institute have uncovered how a build-up of DNA molecules can impact survival chances in people with severe COVID-19 or sepsis, and have developed a tool that could be used to identify the patients ...
Nov 17, 2022
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Patients with chronic obstructive pulmonary disease (COPD) are more likely to have coronary heart disease (CHD), but no specific phenotypes have a higher risk, according to a study published online April 27 in PLOS ONE.
May 17, 2022
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