(Medical Xpress)—UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms – also known as the body clock – modify energy metabolism and also have identified novel compounds that control ...
Jan 22, 2013
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The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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The process researchers use to generate induced pluripotent stem cells (iPSCs)—a special type of stem cell that can be made in the lab from any type of adult cell—is time consuming and inefficient. To speed things up, ...
Sep 25, 2012
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(Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases.
Jul 9, 2012
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Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation.
Mar 15, 2012
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Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 9, 2012
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A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of ...
Sep 27, 2011
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UC Irvine researchers have found a new approach to the creation of customized therapies for virulent flu strains that resist current antiviral drugs.
Jul 12, 2011
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High-protein diets, known as paleolithic diets, are popular. Using mouse models, scientists at the University of Geneva (UNIGE) have studied their impact. While effective in regulating weight and stabilizing diabetes, these ...
Jul 17, 2024
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A study led by an Oregon State University pharmaceutical sciences researcher has produced a proof of principle for a new "universal" means of treating COVID-19.
Oct 18, 2022
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