Medical research

Researchers observe protein degradation in intact brain cells

Neurodegenerative diseases like Alzheimer's, Huntington's or Parkinson's are caused by defect and aggregated proteins accumulating in brain nerve cells that are thereby paralyzed or even killed. In healthy cells this process ...

Medical research

Molecule acts as umpire to make tough life-or-death calls

Researchers have demonstrated that an enzyme required for animal survival after birth functions like an umpire, making the tough calls required for a balanced response to signals that determine if cells live or die. St. Jude ...

Medical research

SIRT5 regulation of proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study published in the Dec. 3rd 2013 issue of ...

Oncology & Cancer

Study identifies new drug target in deadly form of leukemia

A research team led by the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore has identified ways to inhibit the function of a key protein linked to stem cell-like behavior in terminal-stage chronic myeloid leukemia ...

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