Individual cells in the human body develop progressively over time, ultimately becoming specialized in specific functions. This process, known as cell differentiation or specialization, is central to the formation of distinct ...
Neurological disorders, such as trauma, stroke, epilepsy, and various neurodegenerative diseases, often lead to the permanent loss of neurons, causing significant impairments in brain function. Current treatment options are ...
Jul 4, 2024
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Determining the genetic and epigenetic factors that influence brain folding is the objective of the latest study co-led by the Neurogenesis and Cortical Expansion laboratory, directed by researcher Víctor Borrell at the ...
Jun 11, 2024
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Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.
Jun 10, 2024
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Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this definition has evolved to focus ...
May 31, 2024
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Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors. One reason for the ...
May 30, 2024
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A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member ...
May 23, 2024
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Firefighters may have an increased risk of prostate cancer due to on-the-job chemical exposures, according to new research from the University of Arizona Mel and Enid Zuckerman College of Public Health and University of Michigan ...
May 7, 2024
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Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that ...
May 3, 2024
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For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.
May 2, 2024
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