Oncology & Cancer

Epigenetic 'priming' boosts ovarian cancer immunotherapy

An epigenetic inhibitor can boost immune system activity in patients with ovarian cancer, making them more suitable for treatment with immunotherapy, according to a Northwestern Medicine study published in the Journal of ...

Psychology & Psychiatry

A new way to treat PTSD?

Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...

Medical research

How cells keep gene silencing in check

Long considered 'junk," non-coding RNAs have emerged as important regulators of diverse cellular processes, including the silencing of genes. Working in yeast, researchers from the Bühler group have identified more than ...

Health

No level of smoke exposure is safe during pregnancy

Nearly a quarter of pregnant women say they've been around secondhand smoke—in their homes, at work, around a friend or relative—which, according to new research, is linked to epigenetic changes—meaning changes to how ...

Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

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