Genetics

Decoding the language of epigenetic modifications

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study ...

Immunology

Review discusses metabolic reprogramming of T cells

When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...

Oncology & Cancer

Researchers reveal mechanism of drug reactivating tumor suppressors

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...

Neuroscience

Immune genes are altered in Alzheimer's patients' blood

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered. That means the patients' behavior or environment has caused changes that affect the way their genes ...

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