Ophthalmology

Imaging of conjunctival goblet cells helps diagnosis of dry eyes

Goblet cells are epithelial cells that produce mucins and disperse tears which help the surface of eyes maintain their wet environment. Goblet cells are closely related to autoimmune diseases including dry eyes and chemical ...

Ophthalmology

New cell models for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which ...

Diseases, Conditions, Syndromes

Mapping the pathway to gut health in HIV and SIV infections

A UC Davis study found that the damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus, was rapidly repaired within five hours of receiving Lactobacillus ...

Oncology & Cancer

Cancer metastasis: Tumor plasticity counts

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To undergo metastasis, cells must leave the primary tumor, invade the microenvironment, circulate ...

Immunology

A new regulator of B cell development

Interleukin-33 (IL-33) drives inflammatory responses in allergic and nonallergic disease. Epithelial cells in the lungs, gastrointestinal tract and elsewhere release IL-33, which activates the ST2 receptor on immune cell ...

Medical research

Compound in breast milk fights harmful bacteria

Researchers at National Jewish Health and the University of Iowa have identified a compound in human breast milk that fights infections by harmful bacteria while allowing beneficial bacteria to thrive. Human breast milk has ...

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Epithelium

In biology and medicine, an epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body. Many glands are also formed from epithelial tissue. It lies on top of connective tissue, and the two layers are separated by a basement membrane.

In humans, epithelium is classified as a primary body tissue, the other ones being connective tissue, muscle tissue and nervous tissue.

Epithelium is often defined by the expression of the adhesion molecule e-cadherin (as opposed to n-cadherin, which is used by cells of the connective tissue).

Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation and they commonly as a result present extensive apical-basolateral polarity (e.g. different membrane proteins expressed) and specialisation.

This text uses material from Wikipedia, licensed under CC BY-SA