Ophthalmology

New cell models for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which ...

Diabetes

High-fat diet impairs satiation signaling in obese-prone

(HealthDay)—Feeding obese-prone rats a high-fat diet leads to impaired satiation signaling through glucagon-like peptide-1 (GLP-1), a gastrointestinal hormone that suppresses food intake and helps regulate energy balance, ...

Medical research

How the gut gets its villi

Villi are small epithelial protrusions that serve to increase the surface area of the gut for efficient nutrient absorption. The mechanism of their formation during development was recently revealed by a study published in ...

Medical research

Using intestinal organoids to study salmonella

One of the main causes of food poisoning is Salmonella enterica. This bacterium infects cells in the intestinal epithelium that lines our gut, leading to painful stomach cramps, diarrhoea and fever. One major difficulty in ...

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