Oncology & Cancer

Scientists model a peculiar type of breast cancer

Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast. It covers 10 to 15% of all breast cancer cases, has a high risk of late recurrence, unique metastatic ...

Medical research

New discovery in breast cancer treatment

Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

Oncology & Cancer

Mutation leading to biological changes may play role in cancer

A new study from McGill University's Goodman Cancer Research Center (GCRC) has revealed significant biological changes in mice expressing an activated, mutant form of the Estrogen Receptor alpha (ER alpha), shedding new light ...

Oncology & Cancer

The importance of estrogen cycles

Oral contraceptives are implicated in slightly increasing breast cancer risk. This birth control method contains forms of estrogen, a hormone that binds ERalpha (estrogen receptor alpha), to alter the reproductive cycle. ...

Immunology

Higher BPA levels linked to more asthma symptoms in children

Children in low-income neighborhoods in Baltimore tended to have more asthma symptoms when levels of the synthetic chemical BPA (Bisphenol A) in their urine were elevated, according to a study from researchers at the Johns ...

page 1 from 25

Estrogen receptor

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.

This text uses material from Wikipedia, licensed under CC BY-SA