Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor. However, estrogens that stimulate the receptor can also be effective. Building on their ...
May 15, 2023
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If you're a person who gets breast exams, listen up. According to new guidance from medical experts, routine mammograms should now begin at 40 years old—10 years earlier than previously recommended.
May 15, 2023
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Estrogen is known to play an important role in the protection of women's hearts, but once women are postmenopausal and estrogen levels drop, they are at an increased risk of a number of diseases and conditions, including ...
Mar 10, 2023
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New research indicates that for patients with breast cancer, the cancer's stage and receptor status can help clinicians predict whether and when cancer might recur after initial treatment. The findings are published by in ...
Mar 6, 2023
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A large study of military members led by researchers at Duke Health and the Durham VA identified four genes that are linked to an increased risk of suicidal thoughts and behaviors.
Dec 14, 2022
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In patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral crises—those treated with ribociclib plus endocrine therapy had fewer adverse events and a significantly ...
Dec 6, 2022
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While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developing new breast cancers, a new computer modeling study led by researchers at Georgetown Lombardi Comprehensive ...
Dec 1, 2022
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Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types. But TNBCs have a higher risk of recurrence, metastasis and mortality. ...
Nov 30, 2022
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UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women. The findings, published in Science Advances, ...
Nov 1, 2022
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October is Breast Cancer Awareness Month, which makes this a good time to learn about breast cancer types and what your type means.
Oct 5, 2022
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Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
This text uses material from Wikipedia, licensed under CC BY-SA
