Oncology & Cancer
Smoking may impact survival after a breast cancer diagnosis
Researchers have found that smoking may increase the risk of dying early in premenopausal women with breast cancer.
Jun 24, 2015
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Page 16 - News tagged with estrogen receptor
Oncology & Cancer
Study redefines role of estrogen in cervical cancer
Scientists have prior evidence that the hormone estrogen is a major driver in the growth of cervical cancer, but a new study examining genetic profiles of 128 clinical cases reached a surprising conclusion: Estrogen receptors ...
Jun 9, 2015
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Oncology & Cancer
Therapy-resistant breast cancer mechanism revealed
Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved ...
May 26, 2015
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Oncology & Cancer
Investigational ER degrader safe, with early signs of antitumor activity against advanced ER-positive breast cancer
The new investigational estrogen receptor (ER) degrader GDC-0810 was safe and tolerable in postmenopausal women with advanced ER-positive breast cancer, and a subset of the women, all of whom were previously treated with ...
Apr 21, 2015
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Oncology & Cancer
New drug stalls estrogen receptor-positive cancer cell growth and shrinks tumors
An experimental drug rapidly shrinks most tumors in a mouse model of human breast cancer, researchers report in the Proceedings of the National Academy of Sciences. When mice were treated with the experimental drug, BHPI, ...
Mar 30, 2015
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Oncology & Cancer
Interaction of estrogen receptor and coactivators seen for first time
For more than 50 years, Dr. Bert O'Malley, chair of Baylor College of Medicine's department of molecular and cellular biology, has worked to understand the estrogen receptor, how it works and how it partners with other molecules ...
Feb 26, 2015
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Diseases, Conditions, Syndromes
New drug compounds show promise against endometriosis
Two new drug compounds - one of which has already proven useful in a mouse model of multiple sclerosis - appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, ...
Jan 21, 2015
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Oncology & Cancer
Team develops prognostic test for E2F4 in breast cancer
By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center (NCCC), led by Chao Cheng, PhD, have identified a gene signature ...
Jan 7, 2015
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Autism spectrum disorders
Sex hormones may play a part in autism
Higher rates of Autism Spectrum Disorders in males than females may be related to changes in the brain's estrogen signalling, according to research published in the open access journal Molecular Autism.
Sep 8, 2014
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Medical research
Targeting estrogen receptors prevents binge eating in female mice
Binge eating, an eating disorder in which a person frequently consumes unusually large amounts of food in a short period of time, affects about 5 to 10 percent of U.S. adults and is more common in women than men. Researchers ...
Aug 26, 2014
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