Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.
Jun 3, 2020
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Fluctuating estrogen levels may make alcohol more rewarding to female mice, according to new research in JNeurosci. Untangling the involved signaling pathways could unveil sex-based treatments for alcohol use disorders.
Jun 1, 2020
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The same genes that greatly increase the risk of breast cancer in U.S. white women, including women of Ashkenazi Jewish descent, also greatly increase breast cancer risk among African American women. These genes include the ...
May 19, 2020
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A woman's genetic make-up may cause her to gain weight when using a popular form of birth control, according to a study from researchers at the University of Colorado Anschutz Medical Campus.
May 12, 2020
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Activating the G protein-coupled estrogen receptor (GPER)—a receptor found on the surface of many normal and cancer tissues—has been shown to stop pancreatic cancer from growing, but may also make tumors more visible ...
May 4, 2020
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A new study led by Yale Cancer Center (YCC) researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete ...
Apr 28, 2020
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Can women in menopause get the benefits of hormone replacement therapy without the risks? A new UCLA study conducted with mice points in that direction, but additional research is necessary.
Apr 13, 2020
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The hormone estrogen plays many critical roles in men and women, in both healthy tissues and in cancer. In breast and gynecologic cancers, estrogen sends signals to tumors instructing the cancer cells to grow out of control. ...
Feb 11, 2020
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Eric Prossnitz, Ph.D., and his team hope to help 93 million obese Americans fight their fat.
Feb 6, 2020
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A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as ...
Jan 27, 2020
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