NDORMS researchers have identified a critical axis that controls the formation and behavior of cancer stem cells (CSCs), a subpopulation of cells that influence how lethal the cancer can be, its resistance to chemotherapy, ...
Jun 6, 2024
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A team of researchers, affiliated with UNIST have unraveled the molecular mechanisms behind the activation of multiple inflammasomes and their role in inducing inflammatory cell death. This discovery sheds light on the connection ...
Nov 30, 2023
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The brain contains billions of nerve cells controlling our thoughts, behavior and movements. But in fact, up to 20% of the brain is a mystery to scientists. This is the so-called extracellular space, that is, the environment ...
Nov 9, 2023
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Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer. Patients with melanoma or bladder cancer whose tumor cells lack a functioning version of the gene tend not to respond ...
Sep 28, 2023
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A key challenge in neuroscience is to understand how the brain can adapt to a changing world, even with a relatively static anatomy. The way the brain's areas are structurally and functionally related to each other—its ...
Jun 19, 2023
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In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...
Jun 6, 2023
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A new study has investigated the expression of the primary cilium in mesothelioma, finding that primary cilia is preferentially lost in the more aggressive subtype of mesothelioma and further research may confirm its potential ...
Oct 27, 2022
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Humans have developed four different IgG antibody subclasses that orchestrate protection against invading pathogens. A molecular and cellular understanding of how these contribute to eradication of viral infections may guide ...
May 2, 2022
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A reliable sense of space is essential for daily life and memory formation. Removing sugar coated proteins around neurons in the brains' internal gps makes the mental map of space unstable, shows a study published in the ...
Jan 19, 2021
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The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering ...
Jan 13, 2021
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