Genetics
Gene editing possible for kidney disease
For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalised treatment in the future.
Nov 16, 2018
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Page 8 - News tagged with failure model
Cardiology
Protein central to immune system function new target for treating pulmonary hypertension
A protein with a role in sensing cell damage and viral infections is a new target for the treatment of pulmonary hypertension, or increased blood pressure in the lungs, according to research led by Virginia Commonwealth University ...
Nov 15, 2018
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Genetics
Adipose tissue depots compromise heart health
Researchers from the Institute of Pharmacology of the Charité - Universitätsmediz in Berlin have shown that the release of fatty acids from body fat has a major impact on heart health. By interfering with the body's lipid ...
Jan 25, 2018
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Cardiology
Scientists reverse advanced heart failure in an animal model
Researchers have discovered a previously unrecognized healing capacity of the heart. In a mouse model, they were able to reverse severe heart failure by silencing the activity of Hippo, a signaling pathway that can prevent ...
Oct 4, 2017
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Cardiology
Study hints at experimental therapy for heart fibrosis
Researchers report encouraging preclinical results as they pursue elusive therapeutic strategies to repair scarred and poorly functioning heart tissues after cardiac injury—describing an experimental molecular treatment ...
Aug 14, 2017
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Cardiology
How to trick your heart into thinking you exercise
Researchers have discovered that a protein called cardiotrophin 1 (CT1) can trick the heart into growing in a healthy way and pumping more blood, just as it does in response to exercise and pregnancy. They show that this ...
Aug 8, 2017
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Cardiology
Predictive models may help determine which patients benefit from ICDs
Two predictive models may help cardiologists decide which patients would most benefit from an implantable cardioverter defibrillator (ICD), suggests a new study published today in the Journal of the American College of Cardiology. ...
May 22, 2017
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Cardiology
Cancer-cardiac connection illuminates promising new drug for heart failure
A team of researchers at the Gladstone Institutes uncovered a new strategy to treat heart failure, a leading contributor to mortality and healthcare costs in the United States. Despite widespread use of currently-approved ...
May 17, 2017
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Medical research
Researchers propose noninvasive method to detect bone marrow cancer
For the first time, researchers have shown that using Magnetic Resonance Imaging (MRI) can effectively identify bone marrow cancer (myelofibrosis) in an experimental model.
Nov 14, 2016
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Alzheimer's disease & dementia
Elevating brain protein allays symptoms of Alzheimer's and improves memory
Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online August 25, 2016 in Scientific Reports.
Aug 25, 2016
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