A simple vitamin could successfully treat a rare but potentially fatal genetic disease, according to research led by a Concordia undergraduate student.
Mar 7, 2023
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Nearly 100% of cases of amyotrophic lateral sclerosis—the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease—involve the buildup of a protein called TDP-43.
Feb 27, 2023
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ALS is a fatal neurodegenerative disease causing a rapid loss of motor function, which usually results in a serious condition with early death within a few years. So far, early and precise diagnosis of the disease has been ...
Dec 9, 2020
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A mechanism for amyotrophic lateral sclerosis (ALS) development has been discovered at Umeå University, Sweden. The researchers report that proteins with a defect structure spread the deformation to other proteins. The discovery ...
Sep 4, 2018
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Researchers at Western University have uncovered a unique neurobiological pathway triggered by head trauma which underlies both Chronic Traumatic Encephalopathy (CTE) and Lou Gehrig's disease.
Jan 16, 2018
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Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...
Jul 17, 2017
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New research shows environmental pollutants could affect the chances a person will develop amyotrophic lateral sclerosis, or ALS.
May 9, 2016
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Researchers at Oregon State University announced today that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, for nearly two years in one type of mouse model used ...
Jan 28, 2016
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The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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A study of patients in Denmark suggests that type 2 diabetes may be associated with a reduced risk for the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), according to an article published online by JAMA ...
Jun 1, 2015
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