In the aftermath of a heart attack, cells within the region most affected shut down. They stop beating. And they become entombed in scar tissue. But now, scientists at the Gladstone Institutes have demonstrated that this ...
Aug 22, 2013
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As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune response, increased ...
Feb 15, 2013
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Developmental biologists have learned a great deal about how the human digestive tract functions through many years of studies involving fish, frogs, and rodents along with detailed explorations of individual human cells. ...
May 4, 2023
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Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders—especially neurodevelopmental disorders. Novel information ...
Jan 3, 2023
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Three babies have been born after receiving the world's first spina bifida treatment combining surgery with stem cells. This was made possible by a landmark clinical trial at UC Davis Health.
Oct 6, 2022
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Researchers in Brazil affiliated with the State University of Campinas (UNICAMP), D'Or Institute and the Federal University of Rio de Janeiro (UFRJ) have identified molecular processes that may help explain microcephaly in ...
Sep 19, 2022
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Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases. However, the mechanisms involved in engraftment—when ...
Mar 1, 2022
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For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Today, ...
Apr 9, 2021
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A pilot gene therapy treatment for sickle cell disease, restoring patients' ability to make fetal hemoglobin, has produced good results in the first three patients to receive it. Investigators at Boston Children's Hospital ...
Jan 10, 2020
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Lawmakers clashed over science, ethics and politics at a House hearing Thursday on using fetal tissue in critically important medical research, as the Trump administration reviews the government's ongoing support for such ...
Dec 13, 2018
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