Medical research

Rejuvenated fibroblasts can recover the ability to contract

Fibroblasts are the most common connective tissue cells. They produce the structural framework for animal tissues, synthesise the extracellular matrix and collagen, and play a critical role in wound healing. However, during ...

Medical research

Can vaping scar your lungs? New insights and a possible remedy

Researchers report evidence that the compounds in e-cigarette liquid could potentially cause the body's tissue repair process to go haywire and lead to scarring inside the lungs. The new study, conducted in cell cultures, ...

Medical research

Suspect cells' 'neighbor' implicated in colorectal cancer

Colorectal cancer kills more than 50,000 people a year in the United States alone, but scientists have struggled to find the exact mechanisms that trigger the growth of tumors in the intestine.

Oncology & Cancer

Fibroblasts involved in healing spur tumor growth in cancer

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.

Medical research

Scientists reverse fibrosis in preclinical studies

In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis.

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Fibroblast

A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.

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