Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study published in npj Genomic Medicine, researchers at the University of Notre Dame have found ...
Dec 12, 2023
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Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar ...
Dec 6, 2023
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Myocardial fibrosis is major pathological outcome after myocardial ischemia/reperfusion (MI/R) injury and a major risk factor for heart failure. MI/R injury induces cardiomyocyte damage or even death, which in turn stimulates ...
Sep 19, 2023
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While immunotherapies have shown great promise in treating blood cancers, most clinical trials aimed at treating solid tumors such as pancreatic or lung cancer have failed. Researchers have long thought that solid tumors' ...
Sep 18, 2023
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Fibroblast cells play key roles in the repair of damaged tissue and in pathological scarring. Now, researchers at Vanderbilt University Medical Center have uncovered evidence of their direct involvement in the development ...
Jul 14, 2023
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For solid tumors to grow efficiently, they generally need the help of non-transformed, endogenous cells around them. Through the communication of these cells with one another, networks form in the tumor's environment that ...
Jul 6, 2023
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Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or ...
Jun 6, 2023
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Researchers at NIH's National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries. The technique enables researchers to make tissues for ...
May 16, 2023
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A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, ...
Apr 19, 2023
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A new editorial perspective titled "Cancer-associated fibroblasts: challenges and opportunities" has been published in Oncotarget.
Apr 5, 2023
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