It's the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but until now scientists weren't sure how a specific gene caused these devastating diseases. Now researchers from the University ...
Oct 5, 2015
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A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in ...
Apr 4, 2024
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Ten million new cases of dementia are diagnosed each year but the presence of different dementia forms and overlapping symptoms can complicate diagnosis and delivery of effective treatments. Now researchers from Boston University ...
Jul 8, 2024
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An international team of researchers identified a pathogenic mechanism that is common to several neurodegenerative diseases. The findings suggest that it may be possible to slow the progression of dementia even after the ...
Jul 3, 2014
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Inhibition of the PREP enzyme was successful in stopping the progression of frontotemporal dementia in a mouse model of the disease, according to a new study published in Science Translational Medicine. PREP inhibitor treatment ...
Apr 13, 2023
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IBMPFD is a rare and deadly genetic disorder that has devastated entire families, robbing many of their members of their ability to talk, walk and think clearly.
Mar 16, 2015
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The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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ALS—amyotrophic lateral sclerosis—is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow. In a cruel twist, ...
Aug 20, 2018
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A new diagnostic tool helps clinicians to differentiate between Alzheimer's disease, frontotemporal dementia and mild cognitive impairment. Presented in the doctoral thesis of MD Miguel Ángel Muñoz Ruiz at the University ...
Jun 5, 2014
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A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.
Oct 15, 2019
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