An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline ...
Sep 3, 2020
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193
Researchers have long sought to explain precisely how the most common genetic mutation linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia causes the death of nerve cells. Now, Johns Hopkins Medicine ...
Sep 3, 2020
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An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases. The scientists compared the most common inherited form of amyotrophic lateral ...
May 5, 2020
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In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a ...
Apr 2, 2020
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A blood test that may eventually be done in a doctor's office can swiftly reveal if a patient with memory issues has Alzheimer's disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal ...
Mar 2, 2020
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Researchers at the University of Kentucky's College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.
Jan 10, 2020
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In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD), adding to growing evidence that the loss of brain ...
Oct 14, 2019
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In a great stride toward finding an effective treatment for early-stage neurodegenerative diseases, UC Santa Barbara neurobiologist Kenneth S. Kosik and collaborators have uncovered a "druggable" mechanism of pathological ...
Mar 27, 2019
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Unlike the more common Alzheimer's disease, frontotemporal dementia tends to afflict young people. It accounts for an estimated 20 percent of all cases of early-onset dementia. Patients with the illness typically begin to ...
Dec 13, 2018
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160
MIT biologists have discovered a function of a gene that is believed to account for up to 40 percent of all familial cases of amyotrophic lateral sclerosis (ALS). Studies of ALS patients have shown that an abnormally expanded ...
May 7, 2018
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