The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) - the muscle-crippling neurodegenerative disease that afflicted the late astrophysicist Stephen Hawking and cut short the career of iconic ...
Apr 9, 2018
0
173
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases ...
Jan 18, 2018
0
65
A cellular traffic jam appears to affect neurons in most forms of ALS (amyotrophic lateral sclerosis), researchers at Emory University School of Medicine and Mayo Clinic, Jacksonville have shown.
Jan 8, 2018
0
82
Emory University School of Medicine researchers have developed tools that enable them to detect small proteins called granulins for the first time inside cells. Granulins are of interest to neuroscientists because mutations ...
Aug 14, 2017
0
58
Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Aug 8, 2017
0
68
Scientists from the Gladstone Institutes identified that mutations in a protein commonly linked to frontotemporal dementia (FTD) result in obsessive-like behaviors. They linked these behaviors to immune pathways, implicating ...
Apr 24, 2017
1
42
Led by professor Ludo Van Den Bosch (VIB-KU Leuven), scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal ...
Mar 17, 2017
0
42
For the first time novel expression sites in the brain have been identified for a gene which is associated with motor neuron disease and frontotemporal dementia.
Aug 1, 2016
0
101
Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD). Salsalate ...
Sep 21, 2015
1
117
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...
Jun 8, 2015
2
1336
