Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...
Aug 23, 2019
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New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell demonstrates how genetic insights ...
Oct 27, 2011
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Researchers have created a large new resource of more than 900 genes switched off one-at-a-time in mice to discover which genes are important for a wide range of biological functions such as fertility or hearing.
Jul 18, 2013
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A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65.
Jan 19, 2021
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Last month marked the 10th anniversary of the landmark paper that launched "connectomics", overthrowing the predominant approach to localizing individual functions in the brain in favor of mapping the entirety of the brain's ...
Oct 16, 2015
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An analysis of data collected from patients treated for ischemic stroke at Geisinger shows no disparity in outcomes based solely on sex.
Jan 19, 2021
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A large international study has identified three new gene variants associated with body mass index (BMI) levels in adults. The scientific consortium, numbering approximately 200 researchers, performed a meta-analysis of 46 ...
Oct 25, 2012
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A team led by researchers at the National Institutes of Health has overcome a major biological hurdle in an effort to find improved treatments for patients with a rare disease called methylmalonic acidemia (MMA). Using genetically ...
Jul 29, 2013
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The family of disorders known as ataxia can impair speech, balance and coordination, and have varying levels of severity. Scientists from the Universities of Oxford and Edinburgh have identified a new member of this group ...
Dec 7, 2012
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No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences ...
Sep 5, 2013
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