Medications

New drug target to treat pain from visceral organs

An approved drug for chronic constipation also relieves the pain associated with that condition. New research by Scott Waldman, MD, Ph.D., chair of pharmacology, physiology and cancer biology at Jefferson, demonstrates that ...

Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Cardiology

Effects of dalcetrapib on vascular function

Results of the phase IIb dal-VESSEL study show that dalcetrapib, an investigational molecule which acts on cholesteryl ester transfer protein (CETP), did not impair endothelial function (as indicated by flow-mediated dilatation) ...

Medical research

Right combination of sugars regulates brain development in worms

If the development of our nervous system is disturbed, we risk developing serious neurological diseases, impairing our sensory systems, movement control or cognitive functions. This is true for all organisms with a well-developed ...

Oncology & Cancer

Defects in the packaging of DNA in malignant brain tumors

Glioblastomas grow extremely aggressively into healthy brain tissue and, moreover, are highly resistant to radiation therapy and chemotherapy. Therefore, they are regarded as the most malignant type of brain tumor. Currently ...

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