Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The ...
Aug 28, 2013
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The most common form of heritable cognitive impairment is Fragile X Syndrome, caused by mutation or malfunction of the FMR1 gene. Loss of FMR1 function is also the most common genetic cause of autism. Understanding how this ...
Oct 30, 2011
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Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system's inflammation response to infection. ...
Aug 5, 2020
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Though it's most often associated with disorders like diabetes, Harvard researchers have shown how the signaling pathway of insulin and insulin-like peptides plays another critical role in the body – helping to regulate ...
Feb 26, 2013
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Opioid dependence has become a national crisis with serious impact on economic and social welfare, and numerous casualties. A big goal of ongoing research in combating opioid use disorder is understanding drug withdrawal. ...
Aug 29, 2019
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(Medical Xpress)—One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired ...
Mar 22, 2013
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Researchers at the University of Cincinnati (UC) College of Medicine are part of an international team that has identified how the inactive or latent form of GDF8, a signaling protein also known as myostatin responsible for ...
Jan 19, 2018
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Scientists at Duke-NUS Medical School have identified a gene that controls the behavior of a specific type of cardiac macrophage responsible for excessive scarring during the early phases of common heart diseases or cardiomyopathies. ...
Dec 9, 2022
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A team of international scientists has discovered a new mechanism by which immune cells in the skin function act as the body's 'border control', revealing how these cells sense whether lipid or fat-like molecules might indicate ...
Feb 3, 2015
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An international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in the making, which they hope will advance the future treatment of Alzheimer's disease ...
Nov 26, 2021
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